NSAID choice: lessons from PRECISION

Any Choice for Vulnerable Households? Lessons from Choice-Based Lettings

Supporters of choice-based lettings frequently emphasise the principles of customer empowerment, but does this extend to meaningful choice for vulnerable households? The paper focuses initially on the debate on ‘need’ versus ‘choice’ and applies this to vulnerable households. A brief outline is then provided on how choice-based lettings systems in Britain and The Netherlands have attempted to e...

Lessons from Medicare+Choice for Medicare reform.

C urrent discussions of the future of Medicare include proposals to increase the enrollment of beneficiaries in private health insurance plans. These proposals would provide incentives for beneficiaries to join private plans, rely on more loosely structured health plans such as preferred provider organizations (PPOs), change the way health plans are paid, and in some cases create competition be...

Precision and predictive medicine: lessons learned from our oncology colleagues.

A decade ago, a 64-year-old male presenting with fatigue and anemia and a diagnosis suggested of chronic lymphocytic leukemia would be given a standard therapy with an uncertain prognosis. Today, that same patient undergoing molecular profiling of proteins on their lymphocytes detecting ZAP-70 and CD-38 protein markers determines not only the prognosis but how the therapy should be tailored. Th...

NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models.

Both oxidative damage and inflammation are elevated in brains of Alzheimer's disease (AD) patients, but their pathogenic significance remains unclear. The reduced AD risk associated with high intake of both nonsteroidal anti-inflammatory drugs (NSAIDs) and antioxidants suggests causal roles, but clinical trials in AD patients have yielded only limited or negative results. To test the potential ...

Consumer-choice markets: lessons from FEHBP mental health coverage.